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Medical Journal Articles on POTS
The following list contains a selection of peer reviewed medical journal articles pertaining to Postural Orthostatic Tachycardia Syndrome (POTS). There are many more medical journal articles written about POTS, other than those contained on this list. You can also do your own medical literature search on PubMed.gov, a free service offered by the United States National Institutes of Health.
Summary Articles on POTS
Postural Tachycardia Syndrome: Beyond Orthostatic Intolerance.
Garland EM, Celedonio JE, Raj SR. Curr Neurol Neurosci Rep. 2015 Sep;15(9):60.
Postural Tachycardia Syndrome (POTS)
Raj, SR Circulation 10 June 2013
A review of postural orthostatic tachycardia syndrome.
Carew S, et al. Europace. 2009 Jan; 11(1): 18-25.
Cardiology patient pages. Postural tachycardia syndrome: perspectives for patients.
Grubb BP, et al. Circulation. 2008 Jul 15; 118(3): e61-e62.
Clinical presentation and management of patients with hyperadrenergic postural orthostatic tachycardia syndrome. A single center experience.
Kanjwal K, et al. Cardiol J. 2011; 18(5): 527-531.
Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome.
Freeman R, et al. Clin Auton Res. 2011 Apr; 21(2): 69-72.
Postural orthostatic tachycardia syndrome.
Agarwal AK, et al. Postgrad Med J. 2007 Jul; 83(981): 478-480.
Postural orthostatic tachycardia syndrome: a clinical review.
Johnson JN, et al. Pediatr Neurol. 2010 Feb; 42(2): 77-85.
Postural orthostatic tachycardia syndrome: the Mayo clinic experience.
Thieben MJ, et al. Mayo Clin Proc. 2007 Mar; 82(3): 308-313.
Postural syncope: mechanisms and management.
Vaddadi G, et al. Med J Aust. 2007 Sep 3; 187(5): 299-304.
Postural tachycardia syndrome (POTS).
Low PA, et al. J Cardiovasc Electrophysiol. 2009 Mar; 20(3): 352-358.
Postural tachycardia syndrome-current experience and concepts.
Mathias CJ, et al. Nat Rev Neurol. 2011 Dec 6; 8(1): 22-34.
Postural tachycardia syndrome from a pediatrics perspective.
Medow MS. J Pediatr. 2011 Jan; 158(1): 4-6.
The causes of postural cardiovascular disorders.
Ziegler MG, et al. Hypertension. 2005 Mar; 45(3): 354-355.
The postural tachycardia syndrome.
Medow MS, et al. Cardiol Rev. 2007 Mar/Apr; 15(2): 67-75.
Blood volume perturbations in the postural tachycardia syndrome.
Raj SR, et al. Am J Med Sci. 2007 Jul; 334(1): 57-60.
Abnormal Norepinephrine Clearance and Adrenergic Receptor Sensitivity in Idiopathic Orthostatic Intolerance. Giris, J, et al. Circulation 1999; 99:1706-1712.
Comorbid health conditions in women with syncope.
Ulas UH, et al. Clin Auton Res. 2010 Aug; 20(4): 223-227.
Comorbidities in pediatric patients with postural orthostatic tachycardia syndrome.
Ojha A, et al. J Pediatr. 2011 Jan; 158(1): 20-23.
Effects of exercise training on arterial-cardiac baroreflex function in POTS.
Galbreath MM, et al. Clin Auton Res. 2011 Apr; 21(2): 73-80.
Effect of pregnancy on postural tachycardia syndrome.
Kimpinski K, et al. Mayo Clin Proc. 2010 Jul; 85(7): 639-644.
Exercise performance in adolescents with autonomic dysfunction.
Burkhardt BE, et al. J Pediatr. 2011 Jan; 158(1): 15-19.
Gastric electrical activity becomes abnormal in the upright position in patients with postural tachycardia syndrome.
Safder S, et al. J Pediatr Gastroenterol Nutr. 2010 Sep; 51(3): 314-318.
Menstrual cycle affects renal-adrenal and hemodynamic responses during prolonged standing in the postural orthostatic tachycardia syndrome.
Fu Q, et al. Hypertension. 2010 Jul; 56(1): 82-90.
Orthostatic intolerance and the headache patient.
Mack KJ, et al. Semin Pediatr Neurol. 2010 Jun; 17(2): 109-116.
Outcomes of pregnancy in patients with preexisting postural tachycardia syndrome.
Kanjwal K, et al. Pacing Clin Electrophysiol. 2009 Aug; 32(8): 1000-1003.
Postural tachycardia syndrome complicating pregnancy.
Powless CA, et al. J Matern Fetal Neonatal Med. 2010 Aug; 23(8): 850-853.
Postural orthostatic tachycardia syndrome: dental treatment considerations.
Brooks JK, et al. J Am Dent Assoc. 2006 Apr; 137(4): 488-493.
Psychiatric profile and attention deficits in postural tachycardia syndrome.
Raj V, et al. J Neurol Neurosurg Psychiatry. 2009 Mar; 80(3): 339-344.
Sex, hormones and neuroeffector mechanisms.
Hart EC, et al. Acta Physiol (Oxf). 2011 Sep; 203(1): 155-165.
Sleep disturbances and diminished quality of life in postural tachycardia syndrome.
Bagai K, et al. J Clin Sleep Med. 2011 Apr 15; 7(2): 204-210.
Dysautonomia: Perioperative Implications.
Anesthesiology. 2012 Feb;116;1:205?215
Current Therapies:
A double-blind, placebo-controlled, crossover study of the vascular effects of midodrine in neuropathic versus hyperadrenergic Postural Tachycardia Syndrome
Ross, AJ, et al. Clinical Science Aug 2013
Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome.
Raj SR, et al. Circulation. 2005 May 31; 111(21): 2734-2740.
Acute fluid ingestion in the treatment of orthostatic intolerance - important implications for daily practice. Z'Graggen WJ, et al. Eur J Neurol. 2010 Nov; 17(11): 1370-1376.
Angiotensin II type 1 receptor blockade corrects cutaneous nitric oxide deficit in postural tachycardia syndrome.
Stewart JM, et al. Am J Physiol Heart Circ Physiol. 2008 Jan; 294(1): H466-H473.
Ascorbate improves circulation in postural tachycardia syndrome.
Stewart JM, et al. Am J Physiol Heart Circ Physiol. 2011 Sep; 301(3): H1033-H1042.
Erythropoietin in the treatment of postural orthostatic tachycardia syndrome.
Kanjwal K, et al. Am J Ther. 2010 Sep 10.
Exercise training versus propranolol in the treatment of the postural orthostatic tachycardia syndrome.
Fu Q, et al. Hypertension. 2011 Aug; 58(2): 167-175.
Midodrine hydrochloride is effective in the treatment of children with postural orthostatic tachycardia syndrome.
Chen L, et al. Circ J. 2011 Mar; 75(4): 927-931.
Outcomes in adolescents with postural orthostatic tachycardia syndrome treated with midodrine and beta-blockers.
Lai CC, et al. Pacing Clin Electrophysiol. 2009 Feb; 32(2): 234-238.
Potentially new indication of ivabradine: treatment of a patient with postural orthostatic tachycardia syndrome.
Hersi AS. Open Cardiovasc Med J. 2010 Aug; 4: 166-167.
Pyridostigmine in the treatment of orthostatic intolerance.
Gales BJ, et al. Ann Pharmacother. 2007 Feb; 41(2): 314-318.
Pyridostigmine in the treatment of postural orthostatic tachycardia: a single-center experience.
Kanjwal K, et al. Pacing Clin Electrophysiol. 2011 Jun; 34(6): 750-755.
Symptom improvement in postural orthostatic tachycardia syndrome with the sinus node blocker ivabradine.
Ewan V, et al. Europace. 2007 Dec; 9(12): 1202.
Treatment of autonomic neuropathy, postural tachycardia and orthostatic syncope with octreotide LAR.
Hoeldtke RD, et al. Clin Auton Res. 2007 Dec; 17(6): 334-340.
Treatment of postural tachycardia syndrome: a comparison of octreotide and midodrine.
Hoeldtke RD, et al. Clin Auton Res. 2006 Dec; 16(6): 390-395.
Use of methylphenidate in the treatment of patients suffering from refractory postural tachycardia syndrome.
Kanjwal K, et al. Am J Ther. 2012 Jan; 19(1): 2-6.
Use of octreotide in the treatment of refractory orthostatic intolerance.
Kanjwal K, et al. Am J Ther. 2012 Jan; 19(1): 7-10.
Technical Papers:
What is brain fog? An Evaluation of the symptom in postural tachycardia syndrome
Ross, AJ, et al. Clin Auton Res 2013 Sep 3
Renin-Aldosterone Paradox and Perturbed Blood Volume Regulation Underlying Postural Tachycardia Syndrome.
Raj, S., et al. Circulation. 2005; 111: 1574-1582.
Altered systemic hemodynamic & baroreflex response to angiotensin II in postural tachycardia syndrome.
Mustafa HI, et al. Circ Arrhythm Electrophysiol. 2012 Jan.
A screen of candidate genes and influence of beta2-adrenergic receptor genotypes in postural tachycardia syndrome.
Nickander KK, et al. Auton Neurosci. 2005 Jun; 120(1-2): 97-103.
Familia Orthostatic Tachycardia.
Keller, N and Robertson, D; Cur. Opin. Cardiol 2006; 23:173-179.
[Anxiety in patients with Postural Tachycardia Syndrome]
Wagner, C., et al. Fortschr Neurol Psychiatr. 2012 Aug;80(8):458-62. Article in German.
Baroreceptor unloading in postural tachycardia syndrome augments peripheral chemoreceptor sensitivity and decreases central chemoreceptor sensitivity.
Taneja I, et al. Am J Physiol Heart Circ Physiol. 2011 Jul; 301(1): H173-H179.
Change and significance in the levels of plasma urotensin II and catestatin in children with postural orthostatic tachycardia syndrome.
Liao Y, et al. Beijing Da Xue Xue Bao. 2011 Jun; 43(3): 436-439.
Cutaneous constitutive nitric oxide synthase activation in postural tachycardia syndrome with splanchnic hyperemia.
Stewart JM, et al. Am J Physiol Heart Circ Physiol. 2011 Sep; 301(3): H704-H711.
Decreased microvascular nitric oxide-dependent vasodilation in postural tachycardia syndrome.
Medow MS, et al. Circulation. 2005 Oct; 112(17): 2611-2618.
Decreased upright cerebral blood flow and cerebral autoregulation in normocapnic postural tachycardia syndrome.
Ocon AJ, et al. Am J Physiol Heart Circ Physiol. 2009 Aug; 297(2): H664-H673.
Hyperadrenergic postural tachycardia syndrome in mast cell activation disorders.
Shibao C, et al. Hypertension. 2005 Mar; 45(3): 385-390.
Increased plasma angiotensin II in postural tachycardia syndrome (POTS) is related to reduced blood flow and blood volume.
Stewart JM, et al. Clin Sci (Lond). 2006 Feb; 110(2): 255-263.
Iron insufficiency and hypovitaminosis D in adolescents with chronic fatigue and orthostatic intolerance.
Antiel RM, et al. South Med J. 2011 Aug; 104(8): 609-611.
Other autonomic neuropathies associated with ganglionic antibody.
Sandroni P, et al. Auton Neurosci. 2009 Mar; 146(1-2): 13-17.
Plasma hydrogen sulfide in differential diagnosis between vasovagal syncope and postural orthostatic tachycardia syndrome in children.
Zhang F, et al. J Pediatr. 2012 Feb; 160(2): 227-231.
Transcranial Doppler studies on cerebral autoregulation suggest prolonged cerebral vasoconstriction in a subgroup of patients with orthostatic intolerance.
Lin YJ, et al. Ultrasound Med Biol. 2011 Oct; 37(10): 1554-1560.
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